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The rapid evolution of modern manufacturing systems is driven by the integration of emerging metaverse technologies such as artificial intelligence (AI), digital twin (DT), and different forms of extended reality (XR) like virtual reality (VR), augmented reality (AR), and mixed reality (MR). These advances confront manufacturing workers with complex and evolving environments that demand digital literacy for problem solving in the future workplace. However, manufacturing industry faces a critical shortage of skilled workforce with digital literacy in the world. Further, global pandemic has significantly changed how people work and collaborate digitally and remotely. There is an urgent need to rethink digital platformization and leverage emerging technologies to propel industrial evolution toward human-centered manufacturing metaverse (MfgVerse). This paper presents a forward-looking perspective on the development of MfgVerse, highlighting current efforts in learning factory, cognitive digital twinning, and the new sharing economy of manufacturing-as-a-service (MaaS). MfgVerse is converging into multiplex networks, including a social network of human stakeholders, an interconnected network of manufacturing things or agents (e.g., machines, robots, facilities, material handling systems), a network of digital twins of physical things, as well as auxiliary networks of sales, supply chain, logistics, and remanufacturing systems. We also showcase the design and development of a virtual learning factory for workforce training. Finally, future directions, challenges, and opportunities are discussed for human-centered manufacturing metaverse. We hope this work helps stimulate more comprehensive studies and in-depth research efforts to advance MfgVerse technologies. 

The approval of disease-modifying treatments for Alzheimer's disease demands a rethinking of cognitive screening. Drawing on over 180 stakeholder interviews from the NSF National I-Corps program, this perspective highlights barriers in current workflows, from time constraints in primary care to learning effects in long-term care, and presents innovation pathways centered on AI and digital biomarkers. Speech analysis, in particular, offers a scalable and cost-effective screening tool aligned with existing CPT codes. We outline implementation strategies and emphasize the urgent opportunity to align technological innovation with frontline clinical needs to ensure advances translate into meaningful patient and provider benefit.